HHMI's Janelia Research Campus

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HHMI’s Janelia Research Campus in Ashburn, Virginia, cracks open scientific fields by breaking through technical and intellectual barriers. Our integrated teams of lab scientists and tool-builders pursue a small number of scientific questions with potential for transformative impact. To drive science forward, we share our methods, results, and tools with the scientific community.

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Progress Report on the Cell Observatory Initiative

Progress Report on the Cell Observatory Initiative HHMI's Janelia Research Campus

712 views - 2 months ago

"How Large Language Models impact Bio-image Data Science."

"How Large Language Models impact Bio-image Data Science." HHMI's Janelia Research Campus

190 views - 3 months ago

Sexual dimorphism in the fruit fly central nervous system

Sexual dimorphism in the fruit fly central nervous system HHMI's Janelia Research Campus

411 views - 4 months ago

Example visual-motor pathway in the fruit fly

Example visual-motor pathway in the fruit fly HHMI's Janelia Research Campus

379 views - 4 months ago

Male fruit fly CNS cell types

Male fruit fly CNS cell types HHMI's Janelia Research Campus

903 views - 4 months ago

New research shows how longevity is inherited across generations

New research shows how longevity is inherited across generations HHMI's Janelia Research Campus

251 views - 4 months ago

iGluSnFR4 HHMI's Janelia Research Campus

233 views - 5 months ago

iGABASnFR2 HHMI's Janelia Research Campus

147 views - 5 months ago

FuncEWOrm project C. elegans embryo

FuncEWOrm project C. elegans embryo HHMI's Janelia Research Campus

477 views - 5 months ago

Claire Deo: "Chemigenetic Molecular Tools for Biological Imaging Across Scales"

Claire Deo: "Chemigenetic Molecular Tools for Biological Imaging Across Scales" HHMI's Janelia Research Campus

220 views - 7 months ago

Visual stimulus presentation and simultaneous neural imaging

Visual stimulus presentation and simultaneous neural imaging HHMI's Janelia Research Campus

179 views - 7 months ago

Visualizing neural activities using Rastermap with behavioral annotations.

Visualizing neural activities using Rastermap with behavioral annotations. HHMI's Janelia Research Campus

198 views - 7 months ago

Plasticity in the visual cortex after supervised and unsupervised training

Plasticity in the visual cortex after supervised and unsupervised training HHMI's Janelia Research Campus

202 views - 7 months ago

Andrew Moore: Untangling Intermediate Filament Biology with FilaBuster: A New Tool for Light-Cont...

Andrew Moore: Untangling Intermediate Filament Biology with FilaBuster: A New Tool for Light-Cont... HHMI's Janelia Research Campus

284 views - 8 months ago

Larval zebrafish swim behavior in a closed and open loop

Larval zebrafish swim behavior in a closed and open loop HHMI's Janelia Research Campus

714 views - 9 months ago

Simultaneous recordings of intracellular calcium in astrocytes and extracellular ATP

Simultaneous recordings of intracellular calcium in astrocytes and extracellular ATP HHMI's Janelia Research Campus

239 views - 9 months ago

Deep learning in development biology

Deep learning in development biology HHMI's Janelia Research Campus

232 views - 9 months ago

Rory Power: Advanced custom microscopy development for service provision at the EMBL Imaging Centre

Rory Power: Advanced custom microscopy development for service provision at the EMBL Imaging Centre HHMI's Janelia Research Campus

104 views - 9 months ago

So Far: Content-aware Denoising and Semantic Unmixing

So Far: Content-aware Denoising and Semantic Unmixing HHMI's Janelia Research Campus

164 views - 9 months ago

Transcriptional regulation of metabolism

Transcriptional regulation of metabolism HHMI's Janelia Research Campus

134 views - 9 months ago

Decoding and Translating the Languages of Biology

Decoding and Translating the Languages of Biology HHMI's Janelia Research Campus

152 views - 9 months ago

CellposeSAM: superhuman generalization for cellular segmentation

CellposeSAM: superhuman generalization for cellular segmentation HHMI's Janelia Research Campus

1.1K views - 9 months ago

Towards predictive models of the protein sequence determinants of nuclear condensates

Towards predictive models of the protein sequence determinants of nuclear condensates HHMI's Janelia Research Campus

106 views - 9 months ago

Global views of development

Global views of development HHMI's Janelia Research Campus

146 views - 9 months ago

Genome-scale models of metabolic wiring and rewiring

Genome-scale models of metabolic wiring and rewiring HHMI's Janelia Research Campus

366 views - 9 months ago

The role of signaling beyond the nearest neighbors in preimplantation mouse development

The role of signaling beyond the nearest neighbors in preimplantation mouse development HHMI's Janelia Research Campus

103 views - 9 months ago

Decoding human cell architectures - from spatial proteomics to whole cell modelling

Decoding human cell architectures - from spatial proteomics to whole cell modelling HHMI's Janelia Research Campus

476 views - 9 months ago

Multimodal Data Integration: From Biomarkers to Mechanisms

Multimodal Data Integration: From Biomarkers to Mechanisms HHMI's Janelia Research Campus

163 views - 9 months ago

AI-Accelerated Discovery of Body-Wide Cellular Communication Networks: Creating a New Scientific...

AI-Accelerated Discovery of Body-Wide Cellular Communication Networks: Creating a New Scientific... HHMI's Janelia Research Campus

133 views - 9 months ago

Contrastive Learning for Cross-domain Reconciliation and Discovery

Contrastive Learning for Cross-domain Reconciliation and Discovery HHMI's Janelia Research Campus

56 views - 9 months ago

A platform for multimodal in vivo pooled genetic screens reveals regulators of liver function

A platform for multimodal in vivo pooled genetic screens reveals regulators of liver function HHMI's Janelia Research Campus

135 views - 9 months ago

Intracellular cartography of the human proteome

Intracellular cartography of the human proteome HHMI's Janelia Research Campus

83 views - 9 months ago

Large synthetic image datasets to train foundation models for cell segmentation

Large synthetic image datasets to train foundation models for cell segmentation HHMI's Janelia Research Campus

170 views - 9 months ago

Reformation Is All You Need

Reformation Is All You Need HHMI's Janelia Research Campus

107 views - 9 months ago

Building a Petabyte-Scale Pipeline For AI-Accelerated in vivo Cell Biology

Building a Petabyte-Scale Pipeline For AI-Accelerated in vivo Cell Biology HHMI's Janelia Research Campus

454 views - 9 months ago

Bridging the Tissue and Organelle Scales with Spatial Organellomics

Bridging the Tissue and Organelle Scales with Spatial Organellomics HHMI's Janelia Research Campus

84 views - 9 months ago

Understanding the Sources of Regenerative Capacity In Animals

Understanding the Sources of Regenerative Capacity In Animals HHMI's Janelia Research Campus

139 views - 9 months ago

DELTA measures synaptic turnover of GluA2

DELTA measures synaptic turnover of GluA2 HHMI's Janelia Research Campus

170 views - 10 months ago

New imaging tool maps brain-wide changes in neuronal connections

New imaging tool maps brain-wide changes in neuronal connections HHMI's Janelia Research Campus

551 views - 10 months ago

New method uses DNA barcodes for high throughput RNA and protein detection in deep tissue

New method uses DNA barcodes for high throughput RNA and protein detection in deep tissue HHMI's Janelia Research Campus

536 views - 11 months ago

High throughput protein detection in deep tissue using cycleHCR

High throughput protein detection in deep tissue using cycleHCR HHMI's Janelia Research Campus

639 views - 11 months ago

New imaging method reveals the 3D arrangement of molecules inside cells

New imaging method reveals the 3D arrangement of molecules inside cells HHMI's Janelia Research Campus

319 views - 11 months ago

Predator robots help researchers uncover how larval zebrafish rapidly learn

Predator robots help researchers uncover how larval zebrafish rapidly learn HHMI's Janelia Research Campus

428 views - 11 months ago

Imaging neural activity in the hippocampus during learning

Imaging neural activity in the hippocampus during learning HHMI's Janelia Research Campus

976 views - 1 year ago

Learning to navigate two different virtual corridors

Learning to navigate two different virtual corridors HHMI's Janelia Research Campus

254 views - 1 year ago

Neural activity with increasing number of cells plotted

Neural activity with increasing number of cells plotted HHMI's Janelia Research Campus

244 views - 1 year ago

Cellpose3 can spot cell boundaries even in cloudy conditions

Cellpose3 can spot cell boundaries even in cloudy conditions HHMI's Janelia Research Campus

272 views - 1 year ago

Lysosome trafficking through laddered endoplasmic reticulum and its impact on ER organization

Lysosome trafficking through laddered endoplasmic reticulum and its impact on ER organization HHMI's Janelia Research Campus

157 views - 1 year ago

Stable endoplasmic reticulum - plasma membrane junctions compared with dynamic laddered ER elements

Stable endoplasmic reticulum - plasma membrane junctions compared with dynamic laddered ER elements HHMI's Janelia Research Campus

197 views - 1 year ago

High-resolution imaging reveals ladder-like structure of the endoplasmic reticulum in neurons

High-resolution imaging reveals ladder-like structure of the endoplasmic reticulum in neurons HHMI's Janelia Research Campus

474 views - 1 year ago

3D rendering of an excitatory neuron cell and cilium

3D rendering of an excitatory neuron cell and cilium HHMI's Janelia Research Campus

326 views - 1 year ago

New AI technique generates clear images of thick biological samples without the fancy hardware

New AI technique generates clear images of thick biological samples without the fancy hardware HHMI's Janelia Research Campus

523 views - 1 year ago

Reconstructed 3D movie of ribosome moving through the elongation cycle

Reconstructed 3D movie of ribosome moving through the elongation cycle HHMI's Janelia Research Campus

281 views - 1 year ago

Reconstructed 3D movie of ribosome and binding partners moving through the elongation cycle.

Reconstructed 3D movie of ribosome and binding partners moving through the elongation cycle. HHMI's Janelia Research Campus

373 views - 1 year ago

Astroglial calcium wave in the larval zebrafish brain in response to acute ketamine treatment.

Astroglial calcium wave in the larval zebrafish brain in response to acute ketamine treatment. HHMI's Janelia Research Campus

208 views - 1 year ago

Discouraged zebrafish help reveal how ketamine works in the brain

Discouraged zebrafish help reveal how ketamine works in the brain HHMI's Janelia Research Campus

222 views - 1 year ago

Zebrafish in the assay for futility-induced passivity or “giving up” behavior.

Zebrafish in the assay for futility-induced passivity or “giving up” behavior. HHMI's Janelia Research Campus

301 views - 1 year ago

Fighting female fruit flies

Fighting female fruit flies HHMI's Janelia Research Campus

121 views - 1 year ago

New research finds how fighting female flies focus on their foes

New research finds how fighting female flies focus on their foes HHMI's Janelia Research Campus

120 views - 1 year ago

PetaKit5D: a comprehensive suite of software tools for processing petabyte-scale microscopy data

PetaKit5D: a comprehensive suite of software tools for processing petabyte-scale microscopy data HHMI's Janelia Research Campus

185 views - 1 year ago