In 1991 a group of experienced and highly qualified doctors with an interest in the welfare of children with thalassemia got together and laid the foundation of Pakistan Thalassemia Welfare Society (PATHWEL). It is registered as a non-profit organization vide Letter No VSWA/ICT/135 of 1991 under the Society Registration Act XXI of 1860.
Late Lt Gen Faheem Ahmed Khan (R), HI (M) became the founding President of the Society. In 1992 the first treatment Centre of the Society was started at the PMA House Liaqat Road Rawalpindi. The number of patients benefiting from the treatment Centre gradually started increasing and the space became inadequate. In 2006 with the efforts of Late Lt Gen Fahim Ahmed Khan and many others the Society was able to raise its own five storied building at Tipu Road.