More than 10 million people worldwide suffer from decompensated cirrhosis, often as a result of hepatitis or other chronic liver diseases. In its final stages, decompensated cirrhosis leads to acute-on-chronic liver failure (ACLF), a syndrome characterised by multi-organ failure. Effective treatment of ACLF is an urgent and unmet need. The A-TANGO consortium performs Phase II clinical studies of an innovative therapeutic strategy that targets inflammation and improves hepatocyte proliferation. We call this novel combinatorial therapy G-TAK. In addition, A-TANGO strives to identify reliable biomarkers for better patient stratification and an increased survival rate.
This project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No 945096. This YouTube channel's videos reflect only the view of the producers' and the European Commission is not responsible for any use that may be made of the information they contain.